REF’s picks

AS Roma have the superior squad depth and tactical consistency required to dictate the Rome derby. While Lazio can be stubborn, Roma's -1.25 handicap is the right play here as they are likely to win by a comfortable two-goal margin rather than just scraping a result.

1. 1Superior technical quality and established attacking cohesion in the Roma side.
2. 2Lazio's defensive vulnerabilities when pushed by high-intensity opponents.
3. 3Derby matches can be unpredictable, and a red card or early defensive lapse could keep the score closer than expected.

REF's own opinion, not a guarantee — nothing here is financial or betting advice, and the call is always yours.