REF’s picks

Chicago Fire hold home advantage and sit higher in the table, making them a solid choice to edge past Columbus Crew in this long-standing rivalry. While Columbus arrive on an impressive unbeaten run with strong recent defensive displays, the absence of key players and Chicago's attacking depth should tip the scales.

1. 1Chicago Fire sit higher in the Eastern Conference standings and have home advantage at Soldier Field.
2. 2Columbus Crew bring excellent recent form into the match, winning four of their last five outings.
3. 3The visitors have shown vulnerability away from home against top-half sides despite their recent momentum.

REF's own opinion, not a guarantee — nothing here is financial or betting advice, and the call is always yours.