REF’s picks

St. Louis City are favoured to secure all three points given their superior league position and home form. Portland's defensive absentees make containing the hosts a difficult task.

1. 1Hosts boast more consistent attacking options through Navarro and Holse.
2. 2Portland have struggled to pick up wins consistently away from home.
3. 3Head-to-head encounters frequently feature high-scoring draws that could complicate a clean win.

REF's own opinion, not a guarantee — nothing here is financial or betting advice, and the call is always yours.