REF’s picks

Independiente Medellín hold the upper hand at the Atanasio Girardot against a Once Caldas side missing Dayro Moreno. The hosts have shown strong home intent despite recent mixed results, and Once Caldas struggle to find consistency on the road.

1. 1Medellín sit higher in the table and boast a strong recent head-to-head record against Once Caldas.
2. 2The absence of key talisman Dayro Moreno significantly blunts the visitors' attacking threat.
3. 3Medellín's recent defensive lapses and heavy schedule could expose them to a counter-attack.

REF's own opinion, not a guarantee — nothing here is financial or betting advice, and the call is always yours.